Browse 961 Chemical Products and Raw Materials
Nicotinamide
Nicotinamide, also known as nicotinamide, is an amide compound of nicotinic acid. White crystalline powder; odorless or almost odorless, bitter taste; slightly hygroscopic. Soluble in water or ethanol, soluble in glycerin. Clinically, it is mainly used to prevent and treat pellagra, stomatitis, glossitis, sick sinus syndrome, atrioventricular block and other problems.
Β-Nicotinamide Mononucleotide
β - nicotinamide mononucleotide - nicotinamide mononucleotide, also known as β - nicotinamide mononucleotide (NMN), is the synthetic substrate of coenzyme I, and NMN is also used in anti-aging research. Studies have shown that β - NMN can also regulate the secretion of insulin and the expression of mRNA. β - NMN has a broad application prospect in the field of medical treatment.
Nilotinib
Tasigna is a new kind of tumor targeting drug, which belongs to tyrosine kinase inhibitor. It is used to treat CML patients resistant to imatinib, and has a significant effect. Gleevec is a preferred drug developed by Novartis for the treatment of chronic myelogenous leukemia (CML). Nilotinib is improved from the molecular structure of imatinib, which has a stronger selectivity for bcr-abl kinase activity, a stronger inhibition of tyrosine kinase than imatinib by 30 times, and can inhibit the BCR-ABL mutant kinase activity resistant to imatinib. It can also inhibit the activity of kit and PDGFR kinase.
Nimustine Hydrochloride
Nimostine hydrochloride is a kind of pyrimidine nitrosourea anti-tumor drug. It is the main drug for the treatment of intracranial tumor and meningeal leukemia with other nitrosourea drugs, such as ramustine, carmustine, smeustine, lomustine, formustine, and estraustine sodium phosphate. It belongs to nitrosourea alkylating agent. It can alkylate DNA, prevent DNA repair, change RNA structure and target fine The structure and function of the protein and enzyme of the cell play an anti-tumor role. It can pass through the blood-brain barrier. Animal experiments showed that 7% - 16% of them entered CSF after intravenous drip, and the highest was 30%. After intravenous drip for 5 minutes, the drug began to distribute in the ventricles. After 30 minutes, the drug concentration in the cerebrospinal fluid reached the peak value with a half-life of 0.49 hours. Clinically, it can be used to treat brain tumor, lung cancer, gastric cancer, rectal cancer, esophageal cancer, colon cancer, chronic leukemia and lymphoma, etc. it can be used in combination with other anti-tumor drugs.
Niobium oxide
Niobium pentoxide is used as nickel niobate single crystal to make special optical glass, high and low frequency capacitors and piezoelectric ceramic components. It is also used to produce various niobium alloys for ferroniobium and special steel. It is the raw material for the preparation of niobium and its compounds. It is also used as catalyst and refractory.
Nisin
Nisin, also known as nisin or transliterated as nisin, is a polypeptide substance produced by nisin. It consists of 34 amino acid residues and has a molecular weight of about 3500 Da. Since nisin can inhibit most Gram-positive bacteria and has a strong inhibitory effect on the spores of Bacillus, it is widely used in the food industry as a food preservative. After eating, it is quickly hydrolyzed into amino acids under the physiological pH conditions of the human body and the action of α-chymotrypsin, which will not change the normal flora in the human intestines and produce resistance problems such as other antibiotics, and will not interact with other antibiotics. It is a kind of natural food preservative with high efficiency, non-toxicity, safety and no side effects.
Nisoldipine
Nisoldipine (INN) is a calcium channel blocker of the dihydropyridine class. It sold in the United Statesunder the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels.
Nitenpyram
Nicotinimide is a new product developed in Japan after imidacloprid and imidacloprid. It has excellent absorption, penetration, broad insecticidal spectrum, and is safe and harmless. It is a new generation product for the control of insect pests such as whitefly, aphid, pear Psylla, leafhopper and thrips.
Nitrapyrin
Nitrapyrin is used as nitrogen and soil nitrogen oxide inhibitors and protective agents.
Nitric Acid
Nitric acid (HNO3), also known as aqua fortis and spirit of niter, is a highly corrosive strong mineral acid. Nitric acid is the primary reagent used for nitration – the addition of a nitro group, typically to an organic molecule. Nitric acid is also commonly used as a strong oxidizing agent.
Norfloxacin
Norfloxacin has broad-spectrum and high-efficiency antimicrobial effect, wide treatment range, good oral absorption, low toxicity. It is mainly used in the treatment of urinary tract infection, biliary tract infection and intestinal infection in clinic, with remarkable curative effect.It is suitable for urinary tract infection, gonorrhea, prostatitis, intestinal infection, typhoid fever and other Salmonella infections. Antibiotics, used in the treatment of upper respiratory tract infections, urinary and gastrointestinal tract bacterial infections, biliary tract, surgery, gynecology and obstetrics and other infections have a better effect.
O-Cresolphthalein
White or red yellow crystalline powder. Melting point 223 ℃, soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali, purple, slightly soluble in water, insoluble in benzene.
O-Cresolphthalein Complexone
O-methylphenolphthalein, also known as o-methylphenolphthalein (c22h18o4mol346.38), is a white or yellow powder, easily soluble in ethanol and ether; insoluble in water, soluble in dilute alkali and blue, with a pH value of 8.2-9.8 (color from colorless to red); the maximum absorption peak is 566 (381) mm. O-cresol phthalein complex is not only a metal complex indicator, but also an acid-base indicator. Chelate with calcium and magnesium in acid solution to form purplish red chelate.
O-Phenanthroline
It is a common ligand for spectrometric determination of metals and spectral analysis of CO2 reduction. It can also be used as a redox indicator and a reagent for the determination of ferrotitanium.
O-Phenanthroline Monohydrochloride Monohydrate
Different from phenanthroline, o-phenanthroline hydrochloride is a white acicular crystal with luster. The solubility of water is very high, soluble in ethanol, insoluble in general non-polar solvent.
O-Phthalaldehyde
Yellow needle-like crystals. Melting point 54-56 ℃. Mainly used in medicine, dyes, etc. Amino acid derivatization reagent, fluorescent detection, the reaction can be completed in one minute, but the product is unstable and needs to be detected immediately.
OCTYLPHENYLPOLYETHYLENE GLYCOL
Separation and analysis of hydrocarbon compounds, oxygen-containing compounds (alcohols, esters, ketones), basic and neutral nitrogen-containing compounds, sulfur by using gas chromatography stationary liquid (maximum operating temperature 190℃, solvents are acetone, chloroform, dichloromethane, methanol) alcohol. A versatile nonionic surfactant used to restore membrane components under mild denaturation conditions.
Octabromobisphenol-S
White powder, mainly used as flame retardant.
Octenidine Dihydrochloride
Is a cationic surfactant, active against Gram-positive and negative bacteria.
Octreotide Acetate
Octreotide is anoctapeptide that mimics natural somatostatin pharmacologically, though it is amore potent inhibitor of growth hormone, glucagon, and insulin than thenatural hormone.
Octreotide
Octreotide is a kind of synthetic octapeptide ring compound used in digestive system. It is a homologue of natural somatostatin, has the pharmacological activity of natural somatostatin, and has long-term effect (the half-life of this product is 1.5 hours, and the natural somatostatin is 2-3 minutes). This product has selective inhibitory effect on the secretion of growth hormone, glucagon and insulin, which is stronger than natural somatostatin. The animal test shows that the inhibitory effect of this product on the release of growth hormone is 70 times of natural somatostatin and the inhibitory effect on insulin is 3 times of natural somatostatin after 15 minutes of intravenous injection. It can also inhibit the secretion of gastric acid, amylase, lipase and pepsin. It can slow down the passage time of the gastrointestinal tract, promote the absorption of water and electrolyte, have the contractive effect on the visceral blood vessels, reduce the visceral blood flow, reduce the blood flow of the liver, reduce the portal pressure and blood flow of the portal vein, reduce the excessive secretion of the intestinal tract, and enhance the absorption of water and Na + by the intestinal tract.
Ofloxacin Hydrochloride
Ofloxacin is used to treat infections including: respiratory tract infections,cellulitis,urinary tract infections,prostatitis, anthrax,endocarditis,meningitis,pelvic inflammatory disease,traveler's diarrhea,tuberculosis andplague.
Olaparib
Olapani is a new oral poly ADP ribose polymerase (PARP) inhibitor. PARP includes the most important members of three protein families: PARP1, PARP2 and parp3. PARP enzymes are involved in normal cell homeostasis, such as DNA transcription, cell cycle regulation and DNA repair. The results of olaparine in vitro showed that the single drug treatment or platinum based chemotherapy could inhibit the growth of the selected tumor cell line and the tumor growth of human cancer mice xenotransplantation model. The cytotoxicity and antitumor activity of BRCA deficient mouse tumor cell lines were increased after treatment with olaparine. In vitro studies also showed that the cytotoxicity induced by olapamil may be related to the inhibition of PARP enzyme activity and the increase of parp-dna complex formation, leading to the destruction of cell dynamic balance and cell death.
Opdivo
Used in patients with advanced squamous non-small cell lung cancer (NSCLC) who have been previously treated.
