Nilotinib
Also known as: Nilotinib-d6
Tasigna is a new kind of tumor targeting drug, which belongs to tyrosine kinase inhibitor. It is used to treat CML patients resistant to imatinib, and has a significant effect. Gleevec is a preferred drug developed by Novartis for the treatment of chronic myelogenous leukemia (CML). Nilotinib is improved from the molecular structure of imatinib, which has a stronger selectivity for bcr-abl kinase activity, a stronger inhibition of tyrosine kinase than imatinib by 30 times, and can inhibit the BCR-ABL mutant kinase activity resistant to imatinib. It can also inhibit the activity of kit and PDGFR kinase.
| Payment & Shipping Terms | Supply Capacity | ||
|---|---|---|---|
| Payment Terms: | T/T, WU | Production Capacity: | 1000kg/year |
| Min. Order: | 1 Gram | Packing: | according to the customer's requirements |
| Means of Transport: | Ocean, Air, Land | Delivery Date: | 7 days |
Nilotinib
CAS 641571-10-0
Tasigna is a new kind of tumor targeting drug, which belongs to tyrosine kinase inhibitor. It is used to treat CML patients resistant to imatinib, and has a significant effect. Gleevec is a preferred drug developed by Novartis for the treatment of chronic myelogenous leukemia (CML). Nilotinib is improved from the molecular structure of imatinib, which has a stronger selectivity for bcr-abl kinase activity, a stronger inhibition of tyrosine kinase than imatinib by 30 times, and can inhibit the BCR-ABL mutant kinase activity resistant to imatinib. It can also inhibit the activity of kit and PDGFR kinase.
We can customize according to customer's requirement
if you have any question pls mail us or call us.
| CAS Number | 641571-10-0 |
|---|---|
| Molecular Formula | C28H22F3N7O |
| Molecular Weight | 529.52 |
| Place of Origin | Shandong,China (Mainland) |
| Brand | MOSINTER |
Send an inquiry for Nilotinib
Related products
1-Bromo-3-chloro-2-methylpropane
Application:Used as pharmaceutical intermediates
1-benzyl-2-phenyl-1H-imidazole
Contact MOSINTER for product specifications and supply information.
10-Hydroxycamptothecin
Exemestane is an irreversible steroidal aromatase inhibitors, has similar structure with its substrate,natural androstenedione. And it is the pseudo substrate of aromatase . The inhibition of aromatase to estrogen deprivation is a effective method in the treatment of postmenopausal women with hormone dependent breast cancer.
2-Chlorophenothiazine
Application:Chlorpromazine hydrochloride used as drug intermediates; Pharmaceutical intermediates for the preparation of chlorpromazine, perphenazine.
3-Dimethylamino-2-methylpropyl Chloride Hydrochloride
Application:Used as pharmaceutical intermediates
3-Dimethylaminopropylchloride Hydrochloride
1. Used for synthesis of chlorpromazine, doxepin hydrochloride, chlorprothixene medicine, etc
3-Ethyl-4-methyl-3-pyrrolin-2-one
3-Ethyl-4-methyl-3-pyrrolin-2-one, a five-membered α,β-unsaturated lactam derivative, has various applications in medicinal chemistry. It can be synthesized by employing following as starting materials:[1] • allylamine, via palladium(II)-assisted cyclization • 4-methoxybenzylamine, via a ring-closing-metathesis strategy • 3-ethyl-1-(4-methoxybenzyl)-4-methyl-1,5-dihydro-2H-pyrrol-2- one
5- 1-Hydroxyl-1-methylethyl -2-propyl-imidazol-4-yl Carboxylic Acid Ethyl Ester
[5-(1-Hydroxyl-1-methylethyl)-2-propyl-imidazol-4-yl]carboxylic acid ethyl ester
