Pharmaceutical Chemicals API (267)
Showing 229–240 of 267 products · Page 20 of 23
Tenofovir
Tenofovir is a kind of Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.Tenofovir is a non cyclic nucleoside antiviral medicine, has the role of inhibition of HBV multi enzyme poly and HIV reverse transcriptase, for active ingredient tenofovir tenofovir bisphosphonates can through direct competition with natural DNA substrate combination and inhibit the viral polymerase and through in the human DNA chain termination.
Tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate
Hydrazinecarboxylic acid 2-[[4-(2-pyridinyl)phenyl]methyl]-, 1,1-dimethylethyl ester
Thymidine
Thymidine (deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.
Tiamulin Fumarate
Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci, staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E.coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridium perfringens with no exception are sensitive to tiamulin. Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to 70S ribosomes.
Tibo Lone
Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement medicine, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
Ticagrelor
Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor, which is the main receptor responsible for ADP-induced platelet aggregation. It is used to reduce cardiovascular death and heart attacks in patients with acute coronary syndrome (ACS.) Rapid onset after oral administration, and can effectively improve symptoms of patients with ACS. Thienopyridines is a reversible P2Y12 inhibitor, so it is particularly applicable towards patients who need to undergo anticoagulant therapy before surgery.
Tigecycline
Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal subunit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
Tilmicosin Phosphate
Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
Tobramycin Sulphate
Tobramycin Sulphate is belong to aminoglycoside antibiotics,Character is white or kind of white powder or loose block.Mainly used for various gram-negative bacillus and infection caused by pseudomonas aeruginosa.
Toltrazuril
Toltrazuril is a broad-spectrum anthelmintic for humans and animals. It works by interfering with proteins in either the worm's intestine or absorptive cells. This leads to the worm not being able to absorb sugar (glucose), which are essential for its survival. Therefore the energy stores of the worm are depleted, and this leads to its eventual death within several days.
Topotecan Hydrochloride
Topotecan hydrochloride can inhibit the activity of topoisomerase I, which is needed for DNA replication. After intravenous injection, the product is hydrolyzed in blood and excreted in urine. This product has a rapid serum clearance rate of 62L per hour, widely distributed in the body, with a half-life of about 2-3H. The preclinical test showed that the product had antitumor activity for all kinds of tumors. In phase I clinical trial, the product also has obvious antitumor effect on cisplatin resistant ovarian cancer patients.
Toremifene
Toremifene, a chloroethyl derivative of tamoxifene, can competitively bind to estrogen receptor in breast cancer cell plasma, enter the nucleus to regulate the synthesis of mRNA and protein, and prevent the proliferation and differentiation of cancer cells. It is safe to take orally. The peak plasma concentration is reached within 4 hours. The area under the plasma concentration time curve is directly proportional to the dosage. It is mainly metabolized in the liver. Only a small part of the metabolites are excreted from the kidney, and most of them are excreted from the body through defecation. Therefore, hepatoenterocirculation can occur. It has anti estrogen and anti-tumor effects. This product is bound to estrogen receptor, which can prevent the synthesis of chromosomal genes and the growth of tumor cells caused by estrogen. It is suitable for postmenopausal breast cancer and the treatment of recurrent breast cancer. No matter long-term or short-term drug use, there is no obvious toxicity.
