Pharmaceutical Chemicals API (267)
Showing 253–264 of 267 products · Page 22 of 23
VK2
Vitamin K2 is a collective term for a series of terpene side chain compounds containing 2-methyl-1, 4-naphthoquinone nucleus and a different number of isoprene structural units at the C3 position. According to the carbon on the terpene side chain The number of elements can be divided into K2(10), K2(20), K2(35), K2(40), etc. Vitamin K2 (35) is vitamin K2 with 35 carbon elements on the terpene side chain; vitamin K2 (35) is also known as menadione-7, which is based on the fact that there are 7 isoprene on the terpene side chain The alkene side chain is named.
Valsartan
Valsartan is used for the treatment of resistant hypertension, mild-to-moderate essential hypertension,especially for secondary hypertension caused by kidney damage.It can significantly reduce the high blood pressure patients' proteinuria associated with diabetes or abnormal renal function , and has functions of promoting the excretion of uric acid and renal to protect the kidney.
Vancomycin
Vancomycin is a glycopeptide antibiotics macromolecular structure , vancomycin medicine dint strong, in other antibiotics on bacteria invalid will be used. Mainly used for Staphylococcus aureus (including resistance to penicillin and oxacillin resistant strains), Clostridium difficile, caused by infection and intestinal infection, such as endocarditis and sepsis, pseudomembranous enteritis.
Vandetanib
Vandetanide is a multi-target tyrosine kinase inhibitor, belonging to anilinoquinozoline compounds, known as "second generation Iressa". It not only acts on EGFR, VEGFR and RET tyrosine kinases of tumor cells, but also inhibits other tyrosine kinases and serine / threonine kinases. Vandetanide is the first approved medulloid thyroid cancer treatment drug, suitable for the treatment of unresectable, locally advanced or metastatic medulloid thyroid cancer with symptoms or progression. In a randomized, placebo-controlled clinical trial, vandetanib significantly delayed the progression of locally advanced or metastatic medullary thyroid cancer. The recommended daily dose is 300mg (oral), and the treatment should be stopped when the patient has tolerance to the drug or cannot tolerate its toxicity. The most common adverse reactions are diarrhea, rash, acne, nausea, hypertension, headache, fatigue, anorexia and abdominal pain.
Vemurafenib
Verofinil is a small molecule BRAF kinase inhibitor, which can selectively bind to the ATP binding domain of the mutant BRAF, thus inhibiting the activation of the enzyme. The U.S. Food and Drug Administration (FDA) has approved verofinil for the treatment of malignant melanoma with BRAF gene mutation.
Virginiamycin
Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA(virginiamycin M1) and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination. It is also used in agriculture, specifically in livestock, to accelerate the growth of the animals and to prevent and treat infections.
Vitamin A Acetate
Solubility: this product with cyclohexane or chloroform, ether and petroleum ether can be arbitrary mix,slightly soluble in ethanol, insoluble in water.
Vitamin A
Vitamin A is a group of unsaturated nutritional organic compounds, that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids, and beta-carotene.Vitamin A has multiple functions: it is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision. Vitamin A also functions in a very different role as retinoic acid (an irreversibly oxidized form of retinol), which is an important hormone-like growth factor for epithelial and other cells.
Vitamin D2
Ergocalciferol (vitamin D2) is a form of vitamin D. Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light on ergosterol. Viosterol, the name given to early preparations of irradiated ergosterol, is essentially synonymous with ergocalciferol.
Voglibose
Voglibose is an oral fall blood sugar medicine, can improve postprandial hyperglycemia and diabetes by takeda Japanese company successfully developed, belongs to the alpha glycosidase inhibitor (carbohydrates to delay intestinal drug absorption and achieves hypoglycemic effect), the mechanism of action is in intestine inhibits the disaccharides broken down into simple sugars disaccharides class hydrolase (alpha glycosidase enzymes), and thus delay the digestion and absorption of sugar, so as to improve the postprandial hyperglycemia. Health adults give sugar determination of load after exhaled hydrogen, the results confirmed that the dosage of this drug in clinical under has inhibitory effect on blood glucose increased. Normal rat oral medicine, this product after the inhibition of starch and sucrose, maltose load increased blood sugar, lactose and glucose, fructose and to Portugal after load increased blood sugar without inhibition. In vitro test mechanism, according to a study for the maltase from swine and rat small intestine and sucrase, this inhibitory effect is stronger; On the other hand, the pigs and rats alpha inhibition of pancreatic amylase.
Xtandi
It is used to treat advanced castration tolerance of prostate cancer in men who have spread or relapsed. Well mixed amine for androgen receptor inhibitor, was able to suppress androgen receptors and competitive, and can suppress androgen receptors as well as the nuclear transport receptors interact with the DNA of the in vitro experimental study shows that well mixed amine lu can inhibit proliferation and induce the death of prostate cancer cells in mouse prostate cancer xenograft model experiment well mixed amine lu to shrink the tumor volume , the main metabolites of mixed amine lu for N - methyl well mixed amine, its in vitro with mixed amine lu similar inhibitory activity
