Pharmaceutical Chemicals API (267)
Showing 85–96 of 267 products · Page 8 of 23
Doxycycline Monohydrate
Doxycycline is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. It is useful for bacterial pneumonia, acne, chlamydia infections, early Lyme disease, cholera and syphilis. It is also useful for the treatment of malaria when used with quinine and for the prevention of malaria. Doxycycline can be used either by mouth or intravenously.
Dronedarone Hydrochloride
Dronedarone Hydrochloride (CAS: 141625-93-6)
Efavirenz
Efavirenz is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus (HIV) type 1.
Emtricitabine
Emtricitabine is an analogue of cytidine. The drug works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. By interfering with this process, which is central to the replication of HIV, emtricitabine can help to lower the amount of HIV, or "viral load", in a patient's body and can indirectly increase the number of immune system cells (called T cells or CD4+ T-cells). Both of these changes are associated with healthier immune systems and decreased likelihood of serious illness.
Enramycin
Enramycin or Enduracidin is a polypeptide antibiotic produced by Streptomyces fungicidus. Enramycin is widely used as a feed additive for pigs and chickens to prevent necrotic enteritis induced by Gram-positive gut pathogens. Enramycin acts as an inhibitor of the enzyme, MurG, which is essential for cell wall biosynthesis in Gram-positive bacteria. MurG catalyzes the transglycosylation reaction in the last step of peptidoglycan biosynthesis. Inhibiting this step greatly compromises cell wall integrity leading to cell lysis.
Entecavir Hydrate
Entecavir hydrate is a new kind of cyclopentyl acyl guanosine anti-hepatitis b virus medicine with its pharmacological effects similar as entecavir. It is clinically applied to the treatment of adult chronic hepatitis b in which there is active viral replication, increased serum transaminase ALT or active lesions showed from liver histology.
Epirubicin
Epirubicin is one of the drugs selected to treat solid tumors. It acts directly on DNA, interferes with and prevents DNA replication and transcription. It affects the function of mitochondria by inhibiting the activities of respiratory enzymes such as succinate oxidase and NADPH oxidase. It has been found that it can induce apoptosis of cancer cells, which may occur through the mitochondrial pathway of apoptosis. Due to its excretion through the hepatobiliary system, the patients with liver dysfunction should be reduced to avoid accumulation of poisoning; for patients with moderate liver dysfunction (bilirubin 1.4-3mg / 100ml or BSP retention 9-15%), the dosage should be reduced by 50%; for patients with severe liver dysfunction (bilirubin > 3mg / 100ml or BSP retention > 15%), the dosage should be reduced by 75%; for patients with moderate renal dysfunction, there is no need to reduce the dosage, because Only a small amount of the drug is excreted through the kidney. The usage is intravenous administration. It is suggested to inject normal saline first to check the patency of the infusion tube and after the injection needle is indeed in the vein, then to give medicine through the patency of the infusion tube. This method can reduce the risk of drug spillover and ensure that the vein is flushed with saline after administration. If epirubicin overflows the vein during injection, it will cause serious tissue damage or even necrosis. If the same vein is injected in small vein or repeatedly, it will cause venous sclerosis. It cannot be mixed with heparin, because the chemical properties of the two are not compatible, and precipitation reaction will occur at a certain concentration. It can be used with other anti-tumor drugs, but the dosage of epirubicin should be reduced, not in the same syringe Mixed drugs.
Erlotinib Hydrochloride
Erlotinib hydrochloride is a small molecule reversible inhibitor of epidermal growth factor receptor tyrosine kinase, which is mainly used in the second-line or third-line treatment of locally advanced or metastatic non-small cell lung cancer and the treatment of pancreatic cancer.
Ethambutol
Ethambutol (commonly abbreviated EMB or simply E) is a bacteriostatic antimycobacterial medicine prescribed to treat tuberculosis. It is usually given in combination with other tuberculosis medicine, such as isoniazid, rifampicin and pyrazinamide.
Everolimus
Everolimus is a derivative of sirolimus, also known as 40-o - (2-hydroxyethyl) - rapamycin, or 40-o - (2-hydroxyethyl) - sirolimus. It is a kind of kinase drug that interferes with cell communication and prevents tumor cell growth. It is an oral mammalian rapamycin (mTOR) inhibitor. In the past, it was mainly used to prevent rejection after kidney transplantation and heart transplantation. At present, it can also be used in the treatment of advanced renal cancer patients who have used two inhibitors of vascular endothelial growth factor receptor kinase: SUTENT (Pfizer) and Nexavar (Bayer), with slight side effects.
Exemestane
Exemestane is an irreversible steroidal aromatase inhibitors, has similar structure with its substrate,natural androstenedione. And it is the pseudo substrate of aromatase . The inhibition of aromatase to estrogen deprivation is a effective method in the treatment of postmenopausal women with hormone dependent breast cancer.
Famotidine
Famotidine CAS 76824-35-6 dispronil famodil famoxal , have GMP
