Pharmaceutical Chemicals API (267)
Showing 145–156 of 267 products · Page 13 of 23
Lidocaine
Lidocaine is a first-line drug for the treatment of ventricular arrhythmias caused by acute and severe hemodynamic abnormalities. For some supraventricular arrhythmias, such as bypass-mediated supraventricular tachycardia and acute onset or parasympathetic nerve-mediated cardioversion of atrial fibrillation is also effective. It is widely used for mucosal surface anesthesia (such as before tracheal intubation).
Linifanib
Linifanib (ABT-869) is a structurally novel, potent inhibitor of receptor tyrosine kinases (RTK), vascular endothelial growth factor (VEGF) andplatelet-derived growth factor (PDGF) with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGF receptor beta (PDGFR-β), KDR, and colony stimulating factor 1 receptor (CSF-1R), respectively. It has much less activity (IC50s > 1 μM) against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. In vivo linifanib is effective orally in mechanism-based murine models of VEGF-induced uterine edema (ED50 = 0.5 mg/kg) and corneal angiogenesis (>50%inhibition, 15 mg/kg).
Lisinopril
Lisinopril is the third generation of angiotensin converting enzyme inhibitor. It is enalaprilat lysine derivatives and was used to treat high blood pressure in the US from 1987 as the first-line therapy for anti hypertension medicine.The harmacological action characteristics is similar to enalaprilat (Enalapril), it works fast and the effect time is long.
Lomefloxacin
Lomefloxacin belong fluoroquinolones, in vitro antibacterial activity similar with norfloxacin, ciprofloxacin compared with slightly worse, but its in vivo antibacterial activity, including the role of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus are much better than norfloxacin.
Losartan Potassium
Losartan potassium is a new type of non peptide angiotensin Ⅱ (AT1) receptor antagonist, Losartan potassium has good antihypertensive effect and protect the heart, kidney, brain, the walls of blood vessels and the reversal of myocardial hypertrophy, platoon sodium diuresis and promote uric acid excretion.Low incidence of adverse reactions, the patient can tolerate well.
Madubamycin Ammonium
Maduramicin ammonium salt as a coccidiostat of reactor type Eimeria (Ehrlich), Brinell Ehrlich, Ehrlich giant, gentle Ehrlich, Ehrlich displacement, soft Ehrlich and Ehrlich toxic bacteria They are effective for most Gram-positive bacteria also inhibited. Can be used for chicken feed, the amount of 5 (500 × 104U) g / t, laying off, withdrawal of 5-7 days; inhibit the growth of the amount is more than 6g / t, mixed with other medicine should be cautious.
Manidipine Hydrochloride
For two hydrogen pyridine class calcium antagonist medicine, high selectivity of blood vessels, step-down effect is strong and durable, can increase renal blood flow, central The effect of dirty is weak. Oral absorption, blood drug concentration peak time 1 ~ 2 hours. In the plasma and protein at a rate of 97%. T1/2 for about 5 hours.
Marbofloxacin
Marbofloxacin is a synthetic, bactericidal antimicrobial, belonging to the fluoroquinolone group which acts by inhibition of the DNA gyrase. It is effective against a wide range of Gram positive bacteria and Gram negative bacteria as well as Mycoplasma spp. Marbofloxacin can be used both orally and topically. It is particularly used for infections of the skin, respiratory system and mammary glands in dogs and cats, as well as with urinary tract infections.
Mastinib
Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs. Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In theUSAit is distributed under the name Kinavet and has been available for veterinaries since 2011.
Meglumine
Meglumine is widely used in parenteral pharmaceutical formulations and is generally regarded as a nontoxic material at the levels usually employed as an excipient. As a contrast agent of latent solvent and surfactant.Diagnostic medicine, as a cosolvent and contrast agents.Pan shadow meglumine, fluorine symplectic meglumine and meglumine antimonate.
Methacycline Hydrochloride
Metacycline is a tetracycline antibiotic. It is used as a precursor in the industrial synthesis of doxycycline hyclate. It should not be confused with the antibiotic methicillin.
Methocarbamol
Methocarbamol is used for waist and joint ligament acute sprains, sciatica, hyperplastic spondylitis, rheumatoid arthritis, rheumatoid arthritis, muscle strain, etc.
