Endocrine Drugs API (9)
Showing 1–9 of 9 products · Page 1 of 1
Benzbromarone
Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone.
Bupropion hydrochloride API
New types of antidepressants, there are amino ketone structure, irrelevant to three ring, four ring and monoamine oxidase inhibitors or other standard medicine chemically,belongs to central nervous system medicine.
Mifepristone
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4,9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
Oxytocin
Oxytocin is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored as well as secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain.
Pregnant Mare Serum Gonadotropin
Gonadotropins (or glycoprotein hormones) are protein hormones secreted by gonadotrope cells of the anterior pituitary of vertebrates. This is a family of proteins, which include the mammalian hormones follicle-stimulating hormone (FSH), luteinizing hormone (LH), placental chorionic gonadotropins hCG and eCG and chorionic gonadotropin (CG), as well as at least two forms of fish gonadotropins. These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function.The hormones LH and FSH are secreted by the anterior pituitary gland, while hCG and eCG are secreted by the placenta.
Sitagliptin Phosphate Monohydrate
Acid west his dean was first developed by Merck, Germany won the U.S. food and drug administration approved for the treatment of type 2 diabetes dipeptide base peptidase Ⅳ (DDP - 4) inhibitor medicine, is a new type of diabetes, can increase the body's own ability to reduce high blood sugar levels, inhibit the enzyme activity and relatively improve shortness of naturally occurring intestinal insulin, including sample glucagon peptide 1 promote insulin and glucose dependence peptide levels, increased insulin production is triggering the pancreas and the liver to stop glucose production, and finally the clinical effect of lowering blood sugar concentration. The characteristic of this product is in stimulating insulin secretion, at the same time can reduce hungry feeling, and will not put on weight, also won't hypoglycemia and edema occur, suitable for diabetic patients with poor blood sugar control and frequent hypoglycemia. 552 cases of clinically mild-to-moderate patients with type 2 diabetes, take a daily phosphate west he listed, take 100 milligrams, 12 weeks after can reduce glycated hemoglobin 0.6% - 0.6%
Tibo Lone
Tibolone is a synthetic steroid hormone drug, which is fairly non-selective in its binding profile, acting as an agonist mainly at estrogen receptors, with a preference for ER alpha. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolone has similar or greater efficacy compared to older hormone replacement medicine, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
Voglibose
Voglibose is an oral fall blood sugar medicine, can improve postprandial hyperglycemia and diabetes by takeda Japanese company successfully developed, belongs to the alpha glycosidase inhibitor (carbohydrates to delay intestinal drug absorption and achieves hypoglycemic effect), the mechanism of action is in intestine inhibits the disaccharides broken down into simple sugars disaccharides class hydrolase (alpha glycosidase enzymes), and thus delay the digestion and absorption of sugar, so as to improve the postprandial hyperglycemia. Health adults give sugar determination of load after exhaled hydrogen, the results confirmed that the dosage of this drug in clinical under has inhibitory effect on blood glucose increased. Normal rat oral medicine, this product after the inhibition of starch and sucrose, maltose load increased blood sugar, lactose and glucose, fructose and to Portugal after load increased blood sugar without inhibition. In vitro test mechanism, according to a study for the maltase from swine and rat small intestine and sucrase, this inhibitory effect is stronger; On the other hand, the pigs and rats alpha inhibition of pancreatic amylase.
