Sunitinib
Also known as: SUNITINIBD4 SUNITINIB MALEATE
This drug is a small molecular substance that can inhibit many receptor tyrosine kinases, some of which are involved in the process of tumor growth, pathological angiogenesis and tumor metastasis. By evaluating the activity of sunitinib in inhibiting various kinases (more than 80 kinds of kinases), it is proved that sunitinib can inhibit platelet-derived growth factor receptor, vascular endothelial growth factor receptor, stem cell factor receptor, FMS like tyrosine kinase-3, type 1 colony stimulating factor receptor and neurotrophic factor receptor derived from glial cell line. Biochemical and cellular assays confirmed that sunitinib can inhibit the activity of tyrosine kinase of these receptors, and the inhibition of sunitinib was proved in cell proliferation assay. Biochemical and cellular assays showed that the main metabolites were similar to those of sunitinib.
| Payment & Shipping Terms | Supply Capacity | ||
|---|---|---|---|
| Payment Terms: | T/T, WU | Production Capacity: | 1000kg/year |
| Min. Order: | 1 Gram | Packing: | according to the customer's requirements |
| Means of Transport: | Ocean, Air, Land | Delivery Date: | 7 days |
Sunitinib
CAS 557795-19-4
This drug is a small molecular substance that can inhibit many receptor tyrosine kinases, some of which are involved in the process of tumor growth, pathological angiogenesis and tumor metastasis. By evaluating the activity of sunitinib in inhibiting various kinases (more than 80 kinds of kinases), it is proved that sunitinib can inhibit platelet-derived growth factor receptor, vascular endothelial growth factor receptor, stem cell factor receptor, FMS like tyrosine kinase-3, type 1 colony stimulating factor receptor and neurotrophic factor receptor derived from glial cell line. Biochemical and cellular assays confirmed that sunitinib can inhibit the activity of tyrosine kinase of these receptors, and the inhibition of sunitinib was proved in cell proliferation assay. Biochemical and cellular assays showed that the main metabolites were similar to those of sunitinib.
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| CAS Number | 557795-19-4 |
|---|---|
| Molecular Formula | C26H31FN4O6 |
| Molecular Weight | 514.55 |
| Place of Origin | Shandong,China (Mainland) |
| Brand | MOSINTER |
| Specification | CP/USP/EP |
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