Selumetinib
Also known as: ARRY 142886
Smetinib, developed by AstraZeneca, UK, is used to treat advanced non-small cell lung cancer. Smetinib inhibits the growth of a variety of tumors, including melanoma with b-raf-mutation and non-small cell lung cancer with K-ras mutation (NSCLC), mainly by regulating the level of key protein kinase MEK in the RA Raf-MEK-ERK pathway. It is mainly used for the treatment of cholangiocarcinoma, colorectal cancer and NSCLC. At present, smetinib is in the phase III clinical trial of non-small cell lung cancer.
| Payment & Shipping Terms | Supply Capacity | ||
|---|---|---|---|
| Payment Terms: | T/T, WU | Production Capacity: | 1000kg/year |
| Min. Order: | 1 Gram | Packing: | according to the customer's requirements |
| Means of Transport: | Ocean, Air, Land | Delivery Date: | 7 days |
Selumetinib
CAS 606143-52-6
Smetinib, developed by AstraZeneca, UK, is used to treat advanced non-small cell lung cancer. Smetinib inhibits the growth of a variety of tumors, including melanoma with b-raf-mutation and non-small cell lung cancer with K-ras mutation (NSCLC), mainly by regulating the level of key protein kinase MEK in the RA Raf-MEK-ERK pathway. It is mainly used for the treatment of cholangiocarcinoma, colorectal cancer and NSCLC. At present, smetinib is in the phase III clinical trial of non-small cell lung cancer.
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| CAS Number | 606143-52-6 |
|---|---|
| Molecular Formula | C17H15BrClFN4O3 |
| Molecular Weight | 457.68 |
| Place of Origin | Zhejiang,China (Mainland) |
| Content | 98%min |
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