Polymyxin B Sulphate
Also known as: Mastimyxin
Polymyxin B Sulphate is an antibiotic primarily used for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa. Polymyxin B is composed of a number of related compounds (see "Mixture composition"). It has a bactericidal action against almost all Gram-negative bacilli except the Proteus and Neisseria genera. Polymyxins bind to the cell membrane and alter its structure, making it more permeable. The resulting water uptake leads to cell death. Polymyxins are cationic, basic peptides that act like detergents (surfactants). Side effects include neurotoxicity and acute renal tubular necrosis. Polymyxins are used in the topical first-aid preparation Neosporin.
| Payment & Shipping Terms | Supply Capacity | ||
|---|---|---|---|
| Payment Terms: | T/T, WU | Production Capacity: | 1000kg/year |
| Min. Order: | 1 Gram | Packing: | According to the customer's requirements |
| Means of Transport: | Ocean, Air, Land | Delivery Date: | 7 days |
Polymyxin B Sulphate
CAS 1405-20-5
Polymyxin B Sulphate is an antibiotic primarily used for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa. Polymyxin B is composed of a number of related compounds (see "Mixture composition"). It has a bactericidal action against almost all Gram-negative bacilli except the Proteus and Neisseria genera. Polymyxins bind to the cell membrane and alter its structure, making it more permeable. The resulting water uptake leads to cell death. Polymyxins are cationic, basic peptides that act like detergents (surfactants). Side effects include neurotoxicity and acute renal tubular necrosis. Polymyxins are used in the topical first-aid preparation Neosporin.
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| CAS Number | 1405-20-5 |
|---|---|
| Molecular Formula | C48H84N16O17S |
| Molecular Weight | 1189.3426 |
| Storage | 2-8°C |
| Place of Origin | Zhejiang,China (Mainland) |
| CAS No. | 1405-20-5 |
| Boiling point | 1611°C at 760 mmHg |
| Melting point | 217-220°C (dec.) |
| Flash point | 928.1°C |
| Vapour Pressur | 0mmHg at 25°C |
| Water solubility | 50 mg/mL |
Packaging and storage
Storage: 2-8°C
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