Heart And Cerebral Vessels API

Captopril

Captopril have significant antihypertensive effect for various types of high blood pressure as antihypertensive medicine, and can also improve heart function in patients with congestive heart failure.

Irbesartan

Irbesartan is a Angiotensin Ⅱ receptor inhibitors.Angiotensin Ⅱ receptor divides into two kinds,AT1 and AT2.Irbesartan can inhibit Ang Ⅰ to transform into Ang Ⅱ by blocking the AT1 receptor of AnglI selectively,It can also antagonism AT1 specifically.Antagonism between the AT1 is AT2 8500 times.By blocking the combination of Ang Ⅱ and AT1,it can inhibit vascular contraction and the release of aldosterone,then lower the blood pressure.

Lisinopril

Lisinopril is the third generation of angiotensin converting enzyme inhibitor. It is enalaprilat lysine derivatives and was used to treat high blood pressure in the US from 1987 as the first-line therapy for anti hypertension medicine.The harmacological action characteristics is similar to enalaprilat (Enalapril), it works fast and the effect time is long.

Losartan Potassium

Losartan potassium is a new type of non peptide angiotensin Ⅱ (AT1) receptor antagonist, Losartan potassium has good antihypertensive effect and protect the heart, kidney, brain, the walls of blood vessels and the reversal of myocardial hypertrophy, platoon sodium diuresis and promote uric acid excretion.Low incidence of adverse reactions, the patient can tolerate well.

Ticagrelor

Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor, which is the main receptor responsible for ADP-induced platelet aggregation. It is used to reduce cardiovascular death and heart attacks in patients with acute coronary syndrome (ACS.) Rapid onset after oral administration, and can effectively improve symptoms of patients with ACS. Thienopyridines is a reversible P2Y12 inhibitor, so it is particularly applicable towards patients who need to undergo anticoagulant therapy before surgery.

Valsartan

Valsartan is used for the treatment of resistant hypertension, mild-to-moderate essential hypertension,especially for secondary hypertension caused by kidney damage.It can significantly reduce the high blood pressure patients' proteinuria associated with diabetes or abnormal renal function , and has functions of promoting the excretion of uric acid and renal to protect the kidney.