Guanoxan Sulfate

CAS 5714-04-5

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Category: Pharmaceutical Chemicals APISubcategory: Circulatory System Drugs APIProduct ID: guanoxan-sulfate-5714-04-5
Payment & Shipping Terms Supply Capacity
Payment Terms: T/T, WU Production Capacity: 500Ton/year
Min. Order: 1 Gram Packing: according to the customer's requirements
Means of Transport: Ocean, Air, Land Delivery Date: 7 days

Guanoxam (CAS: 5714-04-5)

Item Index
Molecular Formula C10H13N3O2·1/2H2SO4
Molecular Weight 256.27
Specification CP/USP/EP
Appearance White crystalline powder
Content ≤98.0%

Methods of Manufacturing

REACTION OF 6-AMINO-4-CHLORO-N'-METHYL-M-BENZENEDISULFONAMIDE WITH THE DIMETHYL ACETAL OF 2,2,2-TRIFLUOROETHYLMERCAPTOACETALDEHYDE IN ETHYLENE GLYCOL DIMETHYL ETHER IN THE PRESENCE OF A CATALYST

5-Chloroaniline-2,4-disulfonamide + 2,2,2-trifluoroethanol + mercaptoacetaldehyde (sulfide formation/carbonyl condensation/methylation).

Biomedical Effects and Toxicity

Pharmacological Action

Medicine used in the treatment of acute or chronic vascular HYPERTENSIONregardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

CAS Number 5714-04-5
Molecular Formula C10H13N3O2 1/2H2SO4
Molecular Weight 256.27
Place of Origin Shandong,China (Mainland)
Brand MOSINTER
Specification CP/USP/EP
Melting point 205-208℃
Soluble soluble
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