Coenzyme A

CAS 85-61-0

Also known as: Coenzyme ASH

Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation ofpyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate. In humans, CoA biosynthesis requires cysteamine, pantothenate, andadenosine triphosphate (ATP).

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Category: Pharmaceutical Chemicals APISubcategory: Digestive System Drugs APIProduct ID: coenzyme-a-85-61-0
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Payment Terms: T/T, WU Production Capacity: 500 kg /year
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Coenzyme a

CAS: 85-61-0

Item Index
Molecular Formula C21H36N7O16P3S
Molecular weight 767.54
Specification CP/USP/EP
Appearance White to light yellow powder
Storage Condition −20°C

Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation ofpyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester, such as acetyl-CoA) as a substrate. In humans, CoA biosynthesis requires cysteamine, pantothenate, andadenosine triphosphate (ATP).

Function

Since coenzyme A is, in chemical terms, a thiol, it can react with carboxylic acids to form thioesters, thus functioning as an acyl group carrier. It assists in transferring fatty acids from the cytoplasm to mitochondria. A molecule of coenzyme A carrying an acetyl group is also referred to as acetyl-CoA. When it is not attached to an acyl group, it is usually referred to as 'CoASH' or 'HSCoA'.

Coenzyme A is also the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.

CAS Number 85-61-0
Model MOSINTER
Place of Origin Zhejiang,China (Mainland)
cas 85-61-0
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